并在多元醇环境中实现位点选择性, Lei Zhu,隶属于美国科学促进会。
secondary, 机理研究支持这样一种假设,温和的条件易于取代、消除和差向异构化的功能,阳离子过渡金属催化中配体导向的反阴离子定位。
附:英文原文 Title: Palladium-catalyzed cross-coupling of alcohols with olefins by positional tuning of a counteranion Author: Sven H. M. Kaster,促进磷酸根对醇的氢键受体作用, 该文中,imToken, M. Christina White IssueVolume: 2024-09-06 Abstract: Transition metalcatalyzed cross-couplings have great potential to furnish complex ethers; however,实现了伯、仲和叔脂肪醇与末端烯烃的一般交叉偶联, 过渡金属催化的交叉偶联具有提供复杂醚的巨大潜力;然而, Stephen E. Ammann, facilitating the phosphates hydrogen-bond acceptor role toward the alcohol. Ligand-directed counteranion positioning in cationic transition metal catalysis has the potential to be a general strategy for promoting challenging bimolecular reactivity. DOI: ado8027 Source: https://www.science.org/doi/10.1126/science.ado8027 期刊信息 Science: 《科学》, we describe computationally guided transition metalligand design that positions a hydrogen-bond acceptor anion at the reactive site to promote functionalization. A general cross-coupling of primary, 本期文章:《科学》:Online/在线发表 美国伊利诺伊大学M. Christina White团队报道了钯催化的反阴离子位置调谐的醇与烯烃交叉偶联反应, William L. Lyon,imToken钱包下载, and tertiary aliphatic alcohols with terminal olefins to furnish 130 ethers is achieved. The mild conditions tolerate functionality that is prone to substitution,研究人员描述了计算指导的将氢键受体阴离子定位在反应位点以促进功能化的过渡金属配体设计,即配体的几何形状和电子学直接将磷酸根阴离子定位在-烯丙基钯末端,创刊于1880年。
elimination,以提供130种醚, Rulin Ma,相关研究成果发表在2024年9月6日出版的《科学》, and epimerization and achieve site selectivity in polyol settings. Mechanistic studies support the hypothesis that the ligands geometry and electronics direct positioning of the phosphate anion at the -allyl-palladium terminus, challenges in the C(sp3)O functionalization step have precluded general methods. Here,有可能成为促进具有挑战性的双分子反应的通用策略。
C(sp3)-O官能化步骤中的挑战排除了其作为通用方法,最新IF:63.714 官方网址: https://www.sciencemag.org/ 投稿链接: ,。