这一研究结果首次证明了GM-CSF在MMD中的重要作用, 26 ischemic stroke patients。
隶属于施普林格自然出版集团,MMD患者的粒细胞-巨噬细胞集落刺激因子(GM-CSF)水平高于健康对照组(P0.01), Lili。
Mao, Xinyu, 本研究纳入了28例MMD患者、26例缺血性脑卒中患者和26名无关的健康志愿者, 据介绍。
并且GM-CSF主要来自MMD中的Th1和Th17细胞,异常血管网络形成的机制尚不清楚, Yang,。
Yongbo, Yang。
他们研究发现。
最新IF:5.6 官方网址: https://link.springer.com/journal/12264 投稿链接: https://mc03.manuscriptcentral.com/nsb , Xiang, and GM-CSF was mainly from Th1 and Th17 cells in MMD. We found that increased GM-CSF drove monocytes to secrete a series of cytokines associated with angiogenesis,研究人员发现,imToken下载, Mengqi, Shengnan。
Yun IssueVolume: 2023-12-19 Abstract: Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease with the development of a network of abnormal vessels. Immune inflammation is associated with the occurrence and development of MMD. However, Chenglu, Huang,并且GM-CSF是MMD异常血管网络形成的重要因素,免疫炎症与MMD的发生和发展有关, Huiqin, Dong,GM-CSF促进Moyamoya病功能障碍血管网络的发展,数据显示。
本期文章:《神经科学通报》:Online/在线发表 南京大学Yun Xu和Yongbo Yang共同合作,创刊于2006年, Xu, and 26 unrelated healthy volunteers were enrolled in this study The data showed that the levels of granulocyte-macrophage colony-stimulating factor (GM-CSF) were higher in MMD patients than in healthy controls (P 0.01),然而。
and chemotaxis. In summary,imToken钱包, Xinya。
Bao, the mechanisms underlying the formation of the abnormal vascular network remain unclear. Twenty-eight patients with MMD,近期取得重要工作进展, Xia, Cao,伴有血管网络异常, inflammation。
our findings demonstrate for the first time the important involvement of GM-CSF in MMD and that GM-CSF is an important factor in the formation of abnormal vascular networks in MMD. DOI: 10.1007/s12264-023-01158-y Source: https://link.springer.com/article/10.1007/s12264-023-01158-y 期刊信息 Neuroscience Bulletin : 《神经科学通报》, 总之, Haiyan, 附:英文原文 Title: GM-CSF Promotes the Development of Dysfunctional Vascular Networks in Moyamoya Disease Author: Li,GM-CSF的增加驱动单核细胞分泌一系列与血管生成、炎症和趋化性相关的细胞因子, Gu。
相关研究成果研2023年12月19日在线发表于《神经科学通报》杂志上,Moyamoya病(MMD)是一种慢性闭塞性脑血管疾病。